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Some drugs belonging to this group are approved for use for weight management among obese and overweight people with comorbidities

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Creatine also plays a role in brain energy metabolism, and some research suggests it may support cognitive function

In Japan, treatment of asymptomatic hyperuricemia is recommended to mitigate the risk of chronic diseases such as hypertension, coronary artery disease (CAD), and chronic kidney disease (CKD)

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